Waste management (WM) has more and more become an important issue for the entire world, the waste humans are producing are now almost reaching a breaking-point for what the environment can take. This meaning that it is time to look for an effective management system. Almorza et. al (2002) write that since we live in a world that is more and more increasing its awareness, the waste management question has made many politicians and researchers gain interest. The paper is based on the strategy of integrated and sustainable waste management incorporating waste streams such as municipal, industrial wastes, agriculture wastes, hospital wastes and sludge. Integration refers to all mentioned streams and management at all levels resulting in efficient and transparent system, where there is a clear distinction between legislative and enforcement activities at all managerial levels. This paper focuses primarily in general situation of the solid waste in Albania, in analyze the present situation, problems and difficulties The aim is  to provide the sustainable development from a global perspective and to design the Regional Strategy of Solid Waste Management. Region of Korca in Albania is chosen as a case study area to design the regional   integrated strategy.